A dielectrophoresis microfluidic device for trapping bioparticles at low voltage and frequency / (Record no. 10431)

MARC details
000 -LEADER
fixed length control field 02844nam a22002897a 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20261014132317.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 261014b |||||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1738-1266
040 ## - CATALOGING SOURCE
Transcribing agency DSSC
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Jeong, Jin-Tae
9 (RLIN) 13710
130 ## - MAIN ENTRY--UNIFORM TITLE
Uniform title Journal of Biosystems Engineering
9 (RLIN) 13657
245 ## - TITLE STATEMENT
Title A dielectrophoresis microfluidic device for trapping bioparticles at low voltage and frequency /
Statement of responsibility, etc Jin-Tae Jeong, Hyun-Min Shin, Duwoon Kim, and Kyeong-Hwan Lee
264 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Korea :
Name of publisher, distributor, etc The Korean Society for Agricultural Machinery,
Date of publication, distribution, etc 2016.
300 ## - PHYSICAL DESCRIPTION
Extent pp. 60-65
336 ## - CONTENT TYPE
Content type term text
337 ## - MEDIA TYPE
Media type term unmediated
338 ## - CARRIER TYPE
Carrier type term volume
440 ## - SERIES STATEMENT/ADDED ENTRY--TITLE
Volume number/sequential designation 41(1), 60-65
International Standard Serial Number 1738-1266
500 ## - GENERAL NOTE
General note Purpose: The necessity for precise manipulation of bioparticles has greatly increased in the fields of bioscience, biomedical, and environmental monitoring. Dielectrophoresis (DEP) is considered to be an ideal technique to manipulate bioparticles. The objective of this study is to develop a DEP microfluidic device that can trap fluorescent beads, which mimic bioparticles, at the low voltage and frequency of the sinusoidal signal supplied to the microfluidic device. Methods: A DEP microfluidic device, which is composed of polydimethylsiloxane (PDMS) channels and interdigitated electrode networks, is fabricated to trap fluorescent beads. The geometry of the interdigitated electrodes is determined through computational simulation. To determine the optimum voltage and frequency of the sinusoidal signal supplied to the device, the experiments of trapping beads are conducted at various combinations of voltage and frequency. The performance of the DEP microfluidic device is evaluated by investigating the correlation between fluorescent intensities and bead concentrations. Results: the optimum ratio of the widths between the negative and positive electrodes was 1:4 (20:80 um) at a gap of 20 um between the two electrodes. The DEP electrode networks were fabricated based on this geometry and used for the bead trapping experiments. The optimum voltage and frequency of the supplied signal for trapping fluorescent beads were 15 V and 5 kHz, respectively. The fluorescent intensity of the trapped beads increased linearly as the bead concentration increased. The coefficient of determination (R2) between the fluorescent intensity and the bead concentration was 0.989. Conclusion: It is concluded that the microfluidic device developed in this study is promising for trapping bioparticles, such as a cell or virus, if they are conjugated to beads, and their concentration is quantified.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Bead manipulation
9 (RLIN) 13711
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Bioparticle
9 (RLIN) 13712
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Dielectrophoresis
9 (RLIN) 13713
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Fluorescent intensity
9 (RLIN) 13714
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Microfluidic device
9 (RLIN) 13715
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Periodical Indexing
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